Treatment of arrhythmias in patients with chronic kidney disease: recent pharmacological guidelines
DOI:
https://doi.org/10.62452/4rwh3h49Abstract
The occurrence of arrhythmias in patients with chronic kidney disease represented a significant clinical challenge due to their high prevalence and impact on cardiovascular morbidity and mortality. The aim of this research was to analyze the relationship between both conditions, describe the underlying pathophysiological mechanisms, and identify evidence-based therapeutic strategies. A systematic review was conducted following PRISMA guidelines, based on the analysis of specialized scientific literature. The findings revealed a higher prevalence of arrhythmias in advanced stages of kidney disease and in patients undergoing hemodialysis, with atrial fibrillation being the most frequent. Electrolyte imbalances, chronic inflammation, and autonomic dysfunction were identified as key factors in the onset of arrhythmias. Pharmacological management required individualized adjustments due to the potential toxicity of certain medications in patients with impaired renal function. It was concluded that the relationship between chronic kidney disease and arrhythmias was bidirectional, highlighting the need for a comprehensive approach to slow disease progression and improve cardiovascular outcomes. As a recommendation, the development of specific clinical guidelines and early monitoring strategies was proposed to optimize care for this vulnerable population.
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