Lipid-lowering effect of Cocona extract (Solanum sessiliflorum Dunal) in patients with hypercholesterolemia
DOI:
https://doi.org/10.62452/4tt9ch46Keywords:
Cocona extract, atorvastatin, hypercholesterolemia, lipid-lowering effectAbstract
The cocona (Solanumm sessiliflorum Dunal), is a native plant that grows in the countries of the Amazon basin, its fruit has an orange color with various beneficial properties for health. Despite its wide popular use, no studies have yet been carried out to determine its lipid-lowering activity. This study aimed to determine the comparative efficacy of the lipid-lowering effect of Cocona extract and Atorvastatin, in patients with hypercholesterolemia. The study was quasi-experimental, with a control group, with the participation of 32 new patients with hyperlipidemia of both genders aged 18 years and over, who entered the study voluntarily and with informed consent. Group 1 (n=10) received atorvastatin 20 mg. and group 2 (n=22) received 250 ml of cocona extract (cocona pulp, treated water, pectin and potassium sorbate) daily for 30 days. At the beginning of the study, a blood sample was obtained from all the participants, fasting for at least eight hours, to control total cholesterol (TC), HDL cholesterol (HDLc), LDL cholesterol (LDLc) and VLDL cholesterol, and after Ten days after finishing the treatment, the control was repeated again. SPSS Statics 22 was used for statistical analysis. The results showed a significant decrease in TC (G1: 14.1% and G2: 4.7%), LDL (G1: 5.5% and G2: 2.3%), VLDL (G1: 16.4% and G2: 1.7%) and an increase in HDL (G1: 37.9% and G2: 5.4%). It is concluded that the intake of cocona extract had a lipid-lowering effect, showing that it is an alternative treatment for the management of dyslipidemia.
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