Breastfeeding and configuration of the infant intestinal microbiota: a multicriteria approach

Authors

DOI:

https://doi.org/10.62452/7hwnaz92

Keywords:

Breastfeeding, Gut microbiota, Dysbiosis, Human milk oligosaccharides (HMOs), Immune-mediated diseases

Abstract

This study applies a Multicriteria Analysis (MCA) to assess the influence of breastfeeding on the maturation and composition of the infant gut microbiota, and its association with short- and long-term health outcomes. A systematic review of 120 studies published between 2019 and 2024 across databases such as PubMed, Scielo, and Cochrane was conducted, integrating quantitative and qualitative data using Expert Choice and Promethee-GAIA software. Findings indicate that exclusive breastfeeding for ≥6 months correlates with enhanced microbial diversity (40% increase in richness), predominance of Bifidobacterium (60–80%), and reduced colonization by pathogens like E. coli and C. difficile. Clinically, a 30% reduction in gastrointestinal infections and allergies was observed during the first year, along with a 25% lower risk of type 1 diabetes in childhood. This work underlines the importance of breastfeeding in fostering a balanced microbiota and preventing dysbiosis-related immune disorders.

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References

Álvarez, J., Fernández Real, J. M., Guarner, F., Gueimonde, M., Rodríguez, J. M., Saenz de Pipaon, M., & Sanz, Y. (2021). Microbiota intestinal y salud. Gastroenterología y Hepatología, 44(7), 519–535. https://doi.org/10.1016/j.gastrohep.2021.01.009

Borre Ortiz, Y. M., Cortina Navarro, C., & González Ruíz, G. (2014). Lactancia materna exclusiva: ¿La conocen las madres realmente? Revista Cuidarte, 5(2), 723–730. http://dx.doi.org/10.15649/cuidarte.v5i2.84

Brahm, P., & Valdés, V. (2017). Beneficios de la lactancia materna y riesgos de no amamantar. Revista Chilena de Pediatría, 88, 7–14. https://www.scielo.cl/pdf/rcp/v88n1/en_art01.pdf

Cortes-Macías, E., Selma-Royo, M., García-Mantrana, I., Calatayud, M., González, S., Martínez-Costa, C., & Collado, M. C. (2021). Maternal diet shapes the breast milk microbiota composition and diversity: Impact of mode of delivery and antibiotic exposure. Journal of Nutrition, 151(2), 330–340. https://doi.org/10.1093/jn/nxaa310

Farnaud, S., & Evans, R. W. (2003). Lactoferrin—a multifunctional protein with antimicrobial properties. Molecular Immunology, 40(7), 395–405. https://doi.org/10.1016/S0161-5890(03)00152-4

Meek, J. Y., & Noble, L. (2022). Policy statement: Breastfeeding and the use of human milk. Pediatrics, 150(1), e2022057988. https://doi.org/10.1542/peds.2022-057988

Mendoza López, E. (2005). La importancia de la lactancia materna. Revista Salud Pública Nutrición, 6(1). https://www.medigraphic.com/cgi-bin/new/resumen.cgi?IDARTICULO=7681

Minchala-Urgiles, R. E., Ramírez-Coronel, A. A., Estrella-González, M. de los Á., Altamirano-Cárdenas, L. F., Pogyo-Morocho, G. L., Andrade-Molina, M. C., et al. (2020). La lactancia materna como alternativa para la prevención de enfermedades materno-infantiles: Revisión sistemática. Archivos Venezolanos de Farmacología y Terapéutica, 39(8). https://zenodo.org/records/4543500

Moya-Alvarez, V., & Sansonetti, P. J. (2022). Understanding the pathways leading to gut dysbiosis and enteric environmental dysfunction in infants: The influence of maternal dysbiosis and other microbiota determinants during early life. FEMS Microbiology Reviews, 46(3), fuac004. https://doi.org/10.1093/femsre/fuac004

Osorio, L. M., & Umbarila, A. S. (2015). Microbiota de la glándula mamaria. Pediatría, 48(1), 1–8. https://doi.org/10.1016/j.rcpe.2015.07.001

Pannaraj, P. S., Li, F., Cerini, C., Bender, J. M., Yang, S., Rollie, A., Adisetiyo, H., Zabih, S., Lincez, P. J., Bittinger, K., Bailey, A., Bushman, F. D., Sleasman, J. W., & Aldrovandi, G. M. (2017). Association between breast milk bacterial communities and establishment and development of the infant gut microbiome. JAMA Pediatrics, 171(7), 647–654. https://doi.org/10.1001/jamapediatrics.2017.0378

Salazar, S., Chávez, M., Delgado, X., & Eudis Rubio, T. P. (2009). Lactancia materna. Archivos Venezolanos de Puericultura y Pediatría, 72(4), 163–166. https://ve.scielo.org/scielo.php?script=sci_arttext&pid=S0004-06492009000400010&lng=es&nrm=iso&tlng=es

Soto-Hilario, J. D., Torres-Condori, G. M., Fabián-Flores, F. G., Quispe-Coyla, M., Llanos-de Tarazona, M. I., & Ramírez-Montaldo, R. (2025). Pediatric nursing care: A medical–surgical didactic manual. Sophia Editions.

Turroni, F., Duranti, S., Milani, C., Lugli, G. A., van Sinderen, D., & Ventura, M. (2019). Bifidobacterium bifidum: A key member of the early human gut microbiota. Microorganisms, 7(11), 544. https://www.mdpi.com/2076-2607/7/11/544

Urquizo Aréstegui, R. (2014). Lactancia materna exclusiva: ¿Siempre? Revista Peruana de Ginecología y Obstetricia, 60(2), 171–176. https://doi.org/10.31403/rpgo.v60i132

Published

2026-02-22

How to Cite

Peñaherrera-Ron, M. T., Velasco-Muso, M. V., & Chimbo-Oyaque, A. M. (2026). Breastfeeding and configuration of the infant intestinal microbiota: a multicriteria approach. Revista Metropolitana De Ciencias Aplicadas, 9(2), 98-106. https://doi.org/10.62452/7hwnaz92