Therapeutic adherence and personality: a mixed-methods approach in diverse clinical contexts.

Authors

DOI:

https://doi.org/10.62452/hntqk720

Keywords:

Therapeutic adherence, medical treatment, personality traits, clinical contexts

Abstract

Therapeutic adherence plays a crucial role in the effectiveness of medical treatments and the management of chronic diseases. However, non-adherence remains a significant public health challenge with wide-ranging clinical and social implications. This study aims to analyze the influence of personality on treatment adherence, contributing additional data that highlight the importance of psychological factors in following clinical therapies. The research combined a qualitative approach, through a systematic review of scientific literature based on the Five-Factor Model, with a cross-sectional quantitative analysis conducted on 30 patients with chronic illnesses and neuropsychiatric disorders. The study examined how personality traits affect therapeutic adherence, using a multiple linear regression model to identify relevant patterns according to clinical diagnosis and psychological profile. Responsibility was found to enhance treatment compliance, while neuroticism and impulsivity hinder it. Furthermore, variations in adherence were observed among patients with borderline personality disorder, chronic conditions such as diabetes, and adolescents with ADHD, underscoring the need to tailor medical interventions to each patient’s psychological characteristics. Cross-cutting strategies were proposed to improve therapeutic adherence across diverse clinical settings.

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References

Adachi, T., Tsunekawa, Y., & Tanimura, D. (2022). Association between the Big Five personality traits and medication adherence in patients with cardiovascular disease: A cross-scastroectional study. PLoS One, 17(12), e0278534. https://doi:10.1371/journal.pone.0278534

Anarte Ortiz, M.T., & Varela Moreno, E. (2021) Factores psicológicos implicados en la adherencia de personas con alto riesgo de diabetes mellitus tipo 2 (ARDM2). Anuario de Psicología, 51(3), 166-176. https://doi:10.1344/anpsic2021.51/3.19

Bustos, K., Godoy, M.D., Navarra, J.A., González, M. (2022). Estilo de personalidad y adherencia al tratamiento en pacientes adultos con esclerosis múltiple. Multiple Sclerosis and Related Disorders, 60, e 103699. https://www.sciencedirect.com/science/article/abs/pii/S2211034822002140

Cano, C. (2021). Eficacia de la terapia dialéctica comportamental para el tratamiento del trastorno de personalidad límite. Rev Cient Cienc Salud, 3(2), 126-135. https://doi.org/10.53732/rccsalud/03.02.2021.126

Caqueo Urízar, A., Urzúa, A., Mena Chamorro, P., & Bravo de la Fuente, J. (2021). Effects of Adherence to Pharmacological Treatment on the Recovery of Patients with Schizophrenia. Healthcare (Basel, Switzerland), 9(9), e1230. https://doi.org/10.3390/healthcare9091230

Imbaquingo Castro, J. A. (2022). Estudio de los rasgos de personalidad y su influencia en el desarrollo de síntomas ansiosos en estudiantes de la Carrera de Psicología en Línea, de la Universidad Técnica del Norte [Tesis de grado, Universidad Técnica del Norte].

Jadala, R. P., Temkin, H., Daniel, K. L., & Soutullo, C. A. (2025). Adherencia al tratamiento del trastorno por déficit de atención e hiperactividad (TDAH) en el programa ChAMP UT-Health Houston. Medicina, 85 Suppl 1, 82–89. https://pubmed.ncbi.nlm.nih.gov/40020098/

López Villalobos, J.A., López Sánchez, M.V., Serrano Pintado, I., & Andrés de Llano, J.M. (2023). Rasgos de personalidad en adolescentes con trastorno por déficit de atención con hiperactividad. Revista de la Asociación Española de Neuropsiquiatría, 43(143), 55-71. https://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S0211-57352023000100004

Mirhaj Mohammadabadi, M.S., Mohammadsadeghi, H., Eftekhar Adrebili, M., Partovi Kolour, Z., Kashaninasab, F., Rashedi, V., & Shalbafan, M. (2022). Factors associated with pharmacological and psychotherapy treatments adherence in patients with borderline personality disorder. Frontiers in Psychiatry, 13, e1056050. https://doi.org/10.3389/fpsyt.2022.1056050

Molina Chailán, P.M., & Mendoza Parra, S. (2024). Rasgos de personalidad y adherencia terapéutica en personas con tuberculosis: un estudio transversal. Revista Científica Integrada, 7(1), e202405. https://doi.org/10.59464/2359-4632.2024.3275

Published

2025-12-21

How to Cite

Mayorga-Aldaz, E. C. ., Mata-Chango, C. X. ., & Velastegui-Zurita, D. A. . (2025). Therapeutic adherence and personality: a mixed-methods approach in diverse clinical contexts. Revista Metropolitana De Ciencias Aplicadas, 9(1), 324-332. https://doi.org/10.62452/hntqk720