Initial manifestations and clinical management of juvenile ankylosing spondylitis
DOI:
https://doi.org/10.62452/wztnkg09Keywords:
Juvenile ankylosing spondylitis, early diagnosis, HLA-B27, biologic therapy, rehabilitationAbstract
The early recognition of juvenile ankylosing spondylitis poses a clinical challenge due to its atypical presentation and frequent confusion with other musculoskeletal conditions. Initial symptoms such as persistent lower back pain, morning stiffness, and progressive limitation of mobility are often underestimated, delaying diagnosis and increasing the risk of irreversible structural damage. The integration of clinical manifestations with radiological and serological findings—particularly the identification of the HLA-B27 antigen—is essential for accurate and timely diagnosis. Therapeutic management should focus on inflammation control and functional preservation through nonsteroidal anti-inflammatory drugs, biologic therapy, and physical rehabilitation programs. The psychosocial dimension is also critical, as the emotional impact and adaptation of adolescents to a chronic illness require multidisciplinary support. Patient and family education plays a key role in improving treatment adherence and overall quality of life. In conclusion, early detection and comprehensive management of juvenile ankylosing spondylitis are essential to prevent disabling complications and ensure a favorable long-term functional prognosis.
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